Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321884 | 1.00 | PREP (0.56) | PREPHPGD | |
| SCHEMBL9321893 | 1.00 | PREP (0.56) | PREPHPGD | |
| SCHEMBL9177599 | 0.99 | PREP (0.55) | PREPHPGD | |
| SCHEMBL9323315 | 0.99 | PREP (0.55) | PREPHPGD | |
| SCHEMBL9323319 | 0.99 | PREP (0.55) | PREPHPGD | |
| SCHEMBL9183787 | 0.97 | PREP (0.53) | PREPHPGD | |
| SCHEMBL8313638 | 0.84 | PREP (0.42) | PREPHPGD | |
| SCHEMBL4840543 | 0.83 | CHRM2 (0.45) | PREP | |
| SCHEMBL4795338 | 0.83 | CHRM2 (0.45) | PREPHPGD | |
| SCHEMBL1336739 | 0.83 | CHRM2 (0.45) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618193-B1 | Nitrogen containing bicyclic derivatives as prolyl-endopeptidase inhibitors | ADIR (FR) | 1998-10-21 | — | — | EP | disclosed |
| US-5506237-A | PROLYL-ENDOPEPTIDASE INHIBITOR; USEFUL FOR TREATING OR PREVENTING MEMORY LOSS DUE TO AGING, ANXIETY AND DEPRESSION | ADIR ET COMPAGNIE (FR) | 1996-04-09 | — | — | US | disclosed |
| US-5384322-A | Prolylendopeptidase inhibitors; Alzheimer*s disease; antidepressant and anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1995-01-24 | — | — | US | disclosed |
| EP-0618193-A1 | Nitrogen containing bicyclic derivatives as prolyl-endopeptidase inhibitors | ADIR ET COMPAGNIE (FR) | 1994-10-05 | — | — | EP | disclosed |