Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | STS | P08842 | 9/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16400521 | 0.88 | KMT2A (0.67) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL31706334 | 0.88 | KMT2A (0.58) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL12513264 | 0.84 | KMT2A (0.62) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL12069934 | 0.80 | KMT2A (0.58) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL16405079 | 0.79 | HPGD (0.56) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL3307570 | 0.79 | EPHX1 (0.65) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL12321126 | 0.79 | HPGD (0.59) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL315355 | 0.79 | KMT2A (0.57) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL24392034 | 0.79 | HPGD (0.62) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL1245452 | 0.79 | HPGD (0.62) | KMT2AHPGDPTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817677-A | ANTITHROMBOSIS AGENTS | DR. KARL THOMAE GMBH (DE) | 1998-10-06 | — | — | US | disclosed |
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |