Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16400521 | 0.88 | KMT2A (0.67) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL12513264 | 0.84 | KMT2A (0.62) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL38665800 | 0.81 | GLS (0.50) | HPGDEPHX1NPC1RAB9AALDH1A1 | |
| SCHEMBL2939443 | 0.81 | KMT2A (0.54) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL2939442 | 0.81 | KMT2A (0.54) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL23674877 | 0.81 | HPGD (0.61) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL888755 | 0.80 | HPGD (0.60) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL8549425 | 0.80 | KMT2A (0.58) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL16558896 | 0.79 | EPHX1 (0.65) | KMT2AHPGDPTPN2PTPN1PTPN6 | |
| SCHEMBL315355 | 0.79 | KMT2A (0.57) | KMT2AHPGDPTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011148922-A1 | NOVEL QUINAZOLINE COMPOUND | 田辺三菱製薬株式会社 (JP) | 2011-12-01 | — | — | WO | disclosed |