Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 5/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550587 | 0.90 | FFAR1 (0.47) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8550945 | 0.89 | FFAR1 (0.46) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8546551 | 0.89 | FFAR1 (0.46) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8546158 | 0.88 | PLAT (0.48) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8546827 | 0.87 | PLAT (0.42) | FFAR1MEN1KMT2APLATDAO | |
| SCHEMBL8544251 | 0.86 | FFAR1 (0.48) | FFAR1MEN1KMT2APLATDAO | |
| SCHEMBL8549634 | 0.86 | FFAR1 (0.43) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8550204 | 0.83 | PLAT (0.43) | FFAR1MEN1KMT2APLATDAO | |
| SCHEMBL8546486 | 0.83 | ST14 (0.46) | FFAR1MEN1KMT2AALDH1A1PLAT | |
| SCHEMBL12578796 | 0.82 | FFAR1 (0.58) | FFAR1ALDH1A1MAPTPLATKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |