SCHEMBL8550587

SCHEMBL8550587

Cc1cc(Oc2ccc(Cn3oc(=O)[nH]c3=O)cc2)cc(Oc2ccc(Cn3oc(=O)[nH]c3=O)cc2)c1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.47
PLAT P00750 9/20 0.43
IDH1 O75874 1/20 0.39
ALDH1A1 P00352 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
OPRM1 P35372 1/20 0.35
OPRD1 P41143 1/20 0.35
OPRK1 P41145 1/20 0.35
MAPT P10636 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
ST14 Q9Y5Y6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8549448 0.90 FFAR1 (0.45) FFAR1PLATALDH1A1MEN1KMT2A
SCHEMBL8546551 0.89 FFAR1 (0.46) FFAR1PLATALDH1A1MEN1KMT2A
SCHEMBL8550945 0.89 FFAR1 (0.46) FFAR1PLATALDH1A1MEN1KMT2A
SCHEMBL8546158 0.88 PLAT (0.48) FFAR1PLATALDH1A1MEN1KMT2A
SCHEMBL8546827 0.87 PLAT (0.42) FFAR1PLATMEN1KMT2AMAOA
SCHEMBL8544251 0.86 FFAR1 (0.48) FFAR1PLATMEN1KMT2A
SCHEMBL8549634 0.86 FFAR1 (0.43) FFAR1PLATALDH1A1MEN1KMT2A
SCHEMBL8550204 0.83 PLAT (0.43) FFAR1PLATMEN1KMT2A
SCHEMBL8546486 0.83 ST14 (0.46) FFAR1PLATALDH1A1MEN1KMT2A
SCHEMBL8551265 0.80 FFAR1 (0.42) FFAR1PLATALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0696585-B1 NOVEL BISOXADIAZOLIDINE DERIVATIVE YAMANOUCHI PHARMA CO LTD (JP) 1998-12-16 EP disclosed
US-5643931-A ANTIDIABETIC AGENTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1997-07-01 US disclosed
EP-0696585-A1 NOVEL BISOXADIAZOLIDINE DERIVATIVE YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1996-02-14 EP disclosed