Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549524 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ACARM1PRMT6 | |
| SCHEMBL1438961 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACARM1PRMT6 | |
| SCHEMBL12311675 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACARM1PRMT6 | |
| SCHEMBL1438958 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACARM1PRMT6 | |
| SCHEMBL4747242 | 0.84 | MEN1 (0.56) | ALDH1A1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL8172012 | 0.84 | MEN1 (0.56) | ALDH1A1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL3668459 | 0.84 | CA1 (0.47) | MEN1KMT2AANPEP | |
| SCHEMBL9201083 | 0.84 | CARM1 (0.69) | ALDH1A1MEN1KMT2ACARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL8614402 | 0.83 | MEN1 (0.55) | ALDH1A1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL4747248 | 0.83 | CYP2C9 (0.53) | ALDH1A1MEN1KMT2ACARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |