Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11366815 | 0.87 | HSPA5 (0.33) | — | |
| SCHEMBL25425763 | 0.79 | GABRA1 (0.58) | GABRA1GABRB2MGLLMAPTL3MBTL1 | |
| SCHEMBL36294 | 0.79 | GABRA1 (0.58) | GABRA1GABRB2MGLLMAPTL3MBTL1 | |
| SCHEMBL29390847 | 0.79 | GABRA1 (0.58) | GABRA1GABRB2MGLLMAPTL3MBTL1 | |
| SCHEMBL29957198 | 0.76 | TAAR1 (0.46) | MAPTALDH1A1 | |
| SCHEMBL376960 | 0.76 | TAAR1 (0.46) | MAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL2638008 | 0.76 | GABRA1 (0.55) | GABRA1GABRB2MGLLMAPTL3MBTL1 | |
| SCHEMBL14807864 | 0.76 | GABRA1 (0.55) | GABRA1GABRB2MGLLMAPTL3MBTL1 | |
| Benzene SCHEMBL3122858 | 0.76 | TP53 (0.56) | GABRA1GABRB2MGLLMAPTL3MBTL1 | |
| SCHEMBL7542830 | 0.76 | GABRA1 (0.55) | GABRA1GABRB2MGLLMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432762-A1 | INSECTICIDAL ARYLPYRROLINES | Bayer CropScience AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133336-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | WO | disclosed |