Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.54 |
| ▸ | DRD2 | P14416 | 9/20 | 0.54 |
| ▸ | HTR2A | P28223 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9213148 | 0.85 | HTR1A (0.52) | HTR1ADRD2HTR2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6017140 | 0.84 | CYP2C9 (0.47) | HTR1ADRD2HTR2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8550533 | 0.84 | CYP2C9 (0.47) | HTR1ADRD2HTR2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6017220 | 0.83 | HTR1A (0.49) | HTR1ADRD2HTR2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8550861 | 0.83 | HTR1A (0.49) | HTR1ADRD2HTR2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6017185 | 0.83 | CYP2C9 (0.46) | HTR1ADRD2HTR2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8546875 | 0.83 | CYP2C9 (0.46) | HTR1ADRD2HTR2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8550912 | 0.82 | HTR1A (0.48) | HTR1ADRD2HTR2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8550906 | 0.82 | HTR1A (0.48) | HTR1ADRD2HTR2AMEN1ALDH1A1 | |
| SCHEMBL8544808 | 0.81 | MEN1 (0.51) | HTR1ADRD2HTR2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660832-B1 | SEROTONIN RECEPTOR AGENTS | MERRELL PHARMA INC (US) | 1998-01-14 | — | — | EP | disclosed |
| US-5436246-A | Compounds for treatment of anxiety, depression, migraine, stroke, angina and hypertension | MERRELL DOW PHARMACEUTICALS INC. | 1995-07-25 | — | — | US | disclosed |
| EP-0660832-A1 | SEROTONIN RECEPTOR AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006789-A1 | SEROTONIN RECEPTOR AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-31 | — | — | WO | disclosed |