Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547549 | 0.90 | — | — | |
| SCHEMBL8545627 | 0.88 | MAOB (0.47) | LMNAL3MBTL1MAOBNR4A2 | |
| SCHEMBL7900762 | 0.86 | KMT2A (0.57) | KMT2ASMN1; SMN2MAOBNR4A2FFAR1 | |
| SCHEMBL7900754 | 0.86 | KMT2A (0.57) | KMT2ASMN1; SMN2MAOBNR4A2FFAR1 | |
| SCHEMBL8549662 | 0.84 | MAOB (0.51) | LMNAL3MBTL1KMT2ASMN1; SMN2MAOB | |
| SCHEMBL8551119 | 0.84 | PARP15 (0.45) | LMNAL3MBTL1KMT2AMAOBALOX5 | |
| SCHEMBL8551504 | 0.84 | LMNA (0.45) | LMNAL3MBTL1KMT2AFFAR1ALOX5 | |
| SCHEMBL28292246 | 0.83 | MAOB (0.56) | LMNAL3MBTL1KMT2AMAOBNR4A2 | |
| SCHEMBL8550601 | 0.83 | CYP2D6 (0.53) | — | |
| SCHEMBL8545544 | 0.83 | LMNA (0.44) | LMNAL3MBTL1KMT2AMAOBNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |