Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | TPO | P07202 | 1/20 | 0.38 |
| ▸ | EPX | P11678 | 1/20 | 0.38 |
| ▸ | LPO | P22079 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546076 | 0.87 | HTR2A (0.43) | F2F10FFAR1THRBIDO1 | |
| SCHEMBL27431448 | 0.85 | FFAR1 (0.59) | FFAR1HPGDHTR2ASLC6A4KCNH2 | |
| SCHEMBL8547795 | 0.77 | CARM1 (0.52) | THRBIDO1CARM1PRMT6ALDH1A1 | |
| SCHEMBL8550288 | 0.76 | MRGPRX4 (0.44) | FFAR1GAAHTR2ASLC6A4KCNH2 | |
| SCHEMBL8550863 | 0.73 | THRB (0.37) | THRBIDO1ALDH1A1HPGDHTT | |
| SCHEMBL8545423 | 0.73 | SMN1; SMN2 (0.51) | F2F10FFAR1THRBIDO1 | |
| SCHEMBL2218696 | 0.72 | THRB (0.64) | FFAR1THRBIDO1ALDH1A1GAA | |
| SCHEMBL920137 | 0.71 | PARP10 (0.51) | THRBIDO1 | |
| SCHEMBL8544536 | 0.71 | HTR2A (0.44) | ALDH1A1HTTHTR2ASLC6A4KCNH2 | |
| SCHEMBL921682 | 0.71 | SRD5A2 (0.47) | THRBIDO1ALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |