Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.46 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.46 |
| ▸ | ICMT | O60725 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10088434 | 0.90 | AR (0.65) | ARCYP19A1KCNH2SLC6A4HTR2A | |
| SCHEMBL4171609 | 0.89 | AR (0.70) | ARCYP19A1KCNH2SLC6A4HTR2A | |
| SCHEMBL11088375 | 0.89 | AR (0.54) | ARCYP19A1KCNH2SLC6A4HTR2A | |
| SCHEMBL4168829 | 0.85 | MRGPRX4 (0.50) | ARCYP19A1KCNH2SLC6A4HTR2A | |
| SCHEMBL2747584 | 0.83 | EGFR (0.50) | ARCYP19A1KCNH2SLC6A4HTR2A | |
| SCHEMBL3258951 | 0.83 | EGFR (0.47) | ARCYP19A1KCNH2SLC6A4HTR2A | |
| SCHEMBL920869 | 0.81 | AR (0.54) | ARCYP19A1KCNH2SLC6A4HTR2A | |
| SCHEMBL13875516 | 0.81 | AR (0.62) | ARKCNH2SLC6A4HTR2ASLC6A3 | |
| SCHEMBL10852120 | 0.80 | AR (0.54) | ARKCNH2SLC6A4HTR2AMRGPRX4 | |
| SCHEMBL14334473 | 0.80 | AR (0.54) | ARCYP19A1KCNH2SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |