Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549805 | 0.96 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL213239 | 0.88 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8152668 | 0.85 | PTGS1 (0.52) | PTGS2PTGS1 | |
| SCHEMBL8147501 | 0.84 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL8138706 | 0.81 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL8145237 | 0.79 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL8153075 | 0.79 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL7505718 | 0.78 | PTGS2 (0.54) | PTGS2PTGS1 | |
| Sulfamide SCHEMBL4639002 | 0.78 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL8153086 | 0.78 | PTGS2 (0.48) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | claimed |
| WO-1996036617-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | claimed |