Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547760 | 0.91 | GRIN2B (0.47) | ACHEGRIN2BCARM1PRMT6 | |
| SCHEMBL8548011 | 0.86 | GRIN2B (0.62) | ACHEGRIN2B | |
| SCHEMBL8549221 | 0.85 | GRIN2B (0.57) | ACHEGRIN2B | |
| SCHEMBL8545426 | 0.85 | GRIN2B (0.57) | ACHEGRIN2B | |
| SCHEMBL8543111 | 0.84 | GRIN2B (0.54) | ACHEGRIN2BCARM1PRMT6 | |
| SCHEMBL8544989 | 0.81 | GRIN2B (0.59) | ACHEGRIN2B | |
| SCHEMBL8548698 | 0.81 | GRIN2B (0.47) | GRIN2BCARM1PRMT6ALDH1A1 | |
| SCHEMBL8544371 | 0.81 | GRIN2B (0.47) | GRIN2BCARM1PRMT6ALDH1A1 | |
| SCHEMBL8547693 | 0.81 | GRIN2B (0.47) | GRIN2BCARM1PRMT6ALDH1A1 | |
| SCHEMBL8542863 | 0.81 | GRIN2B (0.47) | GRIN2BCARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5698553-A | Benzylpiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |