Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 5/20 | 0.52 |
| ▸ | HTR2C | P28335 | 3/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8018536 | 0.99 | CYP2D6 (0.52) | CYP2D6CYP2C19HTR2AHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL8019007 | 0.88 | KMT2A (0.57) | CYP2D6CYP2C19HTR2AHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL8025579 | 0.87 | HTR2A (0.54) | CYP2D6CYP2C19HTR2AHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL8025405 | 0.85 | HTR2A (0.51) | CYP2D6CYP2C19HTR2AHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL8023096 | 0.85 | HRH1 (0.61) | CYP2C19HTR2AHTR2CHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL8025211 | 0.84 | HTR2A (0.60) | CYP2D6CYP2C19HTR2AHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL8021159 | 0.84 | HTR2A (0.52) | CYP2D6CYP2C19HTR2AHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL8021166 | 0.84 | HTR2A (0.61) | CYP2D6CYP2C19HTR2AHTR2CHTR7 | |
| SCHEMBL8550993 | 0.83 | HTR2A (0.55) | CYP2D6CYP2C19HTR2AHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL8019192 | 0.82 | HTR2A (0.54) | CYP2D6CYP2C19HTR2AHTR2CHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816356-A1 | 1-(2-(1-piperidinyl)-1-ethyl)-1,3-dihydro-2H-benzimidazole derivatives and their pharmaceutical use | ELI LILLY AND COMPANY LIMITED (GB) | 1998-01-07 | — | — | EP | disclosed |