Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298504 | 0.85 | NPC1 (0.70) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14352146 | 0.85 | NPC1 (0.70) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8550156 | 0.82 | NPC1 (0.62) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8307476 | 0.82 | NPC1 (0.62) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8308063 | 0.82 | NPC1 (0.62) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8550159 | 0.82 | NPC1 (0.62) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8307478 | 0.82 | NPC1 (0.62) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1149438 | 0.81 | NPC1 (0.71) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13495018 | 0.81 | NPC1 (0.71) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29938562 | 0.81 | NPC1 (0.71) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832078-A1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040659-A1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1996-12-19 | — | — | WO | disclosed |