Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 10/20 | 0.55 |
| ▸ | DRD2 | P14416 | 8/20 | 0.55 |
| ▸ | HTR2A | P28223 | 6/20 | 0.55 |
| ▸ | HTR1A | P08908 | 4/20 | 0.55 |
| ▸ | DRD4 | P21917 | 3/20 | 0.55 |
| ▸ | HTR1B | P28222 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809830 | 1.00 | HTR1D (0.55) | HTR1DDRD2HTR2AHTR1ADRD4 | |
| SCHEMBL8554794 | 0.86 | HTR1D (0.53) | HTR1DDRD2HTR2AHTR1ADRD4 | |
| SCHEMBL8591943 | 0.86 | DRD2 (0.74) | HTR1DDRD2HTR2AHTR1ADRD4 | |
| SCHEMBL7403729 | 0.86 | DRD2 (0.74) | HTR1DDRD2HTR2AHTR1ADRD4 | |
| SCHEMBL8590932 | 0.86 | DRD2 (0.74) | HTR1DDRD2HTR2AHTR1ADRD4 | |
| SCHEMBL7401836 | 0.85 | DRD2 (0.74) | HTR1DDRD2HTR2AHTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL7403803 | 0.85 | DRD2 (0.73) | HTR1DDRD2HTR2AHTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL8185555 | 0.85 | DRD2 (0.72) | HTR1DDRD2HTR2AHTR1ADRD4 | |
| SCHEMBL8548563 | 0.82 | HTR1D (0.78) | HTR1DDRD2HTR2AHTR1ADRD4 | |
| SCHEMBL8550170 | 0.82 | HTR1D (0.78) | HTR1DDRD2HTR2AHTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836599-A1 | 1,6-DISUBSTITUTED ISOCHROMANS FOR TREATMENT OF MIGRAINE HEADACHES | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002259-A1 | 1,6-DISUBSTITUTED ISOCHROMANS FOR TREATMENT OF MIGRAINE HEADACHES | PHARMACIA & UPJOHN COMPANY (US) | 1997-01-23 | — | — | WO | disclosed |