Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.58 |
| ▸ | CA1 | P00915 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550466 | 0.92 | SMN1; SMN2 (0.53) | CA2CA1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL11977411 | 0.92 | SMN1; SMN2 (0.53) | CA2CA1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL20200244 | 0.90 | SMN1; SMN2 (0.54) | CA2CA1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL11586020 | 0.90 | CA2 (0.68) | CA2CA1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL15551980 | 0.90 | CA2 (0.68) | CA2CA1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL715116 | 0.86 | SMN1; SMN2 (0.67) | CA2CA1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL77617 | 0.86 | SMN1; SMN2 (0.67) | CA2CA1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL77618 | 0.86 | SMN1; SMN2 (0.67) | CA2CA1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL3050606 | 0.84 | SMN1; SMN2 (0.65) | CA2CA1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL8543787 | 0.82 | CA2 (0.60) | CA2CA1SMN1; SMN2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671385-B1 | Method for handling (2-alkyl) acryloyl isocyanate, method for producing (2-alkyl)acryloyl isocyanate, heterocyclic compound, and method for producing heterocyclic compound | NIPPON PAINT CO LTD (JP) | 1998-10-14 | — | — | EP | disclosed |
| US-5663423-A | Method for handling (2-alkyl) (acryloyl) isocyanate, method for stabilizing (2-alkyl) (acryloyl) isocyanate, method for producing (2-alkyl) (acryloyl) isocyanate, heterocyclic compound, and method for producing heterocyclic compound | NIPPON PAINT CO., LTD (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5532360-A | REACTING WITH AZOMETHINE COMPOUND TO FORM HETEROCYCLIC COMPOUND | NIPPON PAINT CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0671385-A1 | Method for handling (2-alkyl) acryloyl isocyanate, method for producing (2-alkyl)acryloyl isocyanate, heterocyclic compound, and method for producing heterocyclic compound | Nippon Paint Co., Ltd. (JP) | 1995-09-13 | — | — | EP | disclosed |