Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GRK2 | P25098 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255795 | 1.00 | EPHX1 (0.69) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL7771291 | 1.00 | EPHX1 (0.69) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL28651494 | 0.98 | EPHX1 (0.67) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL6689012 | 0.83 | EPHX1 (0.67) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL9458781 | 0.83 | EPHX1 (0.67) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL15307543 | 0.83 | EPHX1 (0.67) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL2533818 | 0.83 | EPHX1 (0.67) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL3343090 | 0.83 | EPHX1 (0.67) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL4071198 | 0.83 | EPHX1 (0.67) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL1692473 | 0.83 | EPHX1 (0.67) | EPHX1MEN1TP53CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693485-B1 | Baccatin derivatives and processes for preparing the same | TANABE SEIYAKU CO (JP) | 1998-06-03 | — | — | EP | disclosed |
| US-5677470-A | CHEMICAL INTERMEDIATES; ANTITUMOR AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0693485-A2 | Baccatin derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1996-01-24 | — | — | EP | disclosed |