SCHEMBL8550820

SCHEMBL8550820

CCCCCCOc1ccc(-c2nc3ccc(CCCCCC)cc3s2)cc1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ATP4A P20648 4/20 0.56
ATP4B P51164 4/20 0.56
APP P05067 7/20 0.46
MAPT P10636 3/20 0.46
RAB9A P51151 2/20 0.46
SULT1A1 P50225 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HTT P42858 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
LMNA P02545 1/20 0.45
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5946619 1.00 ATP4A (0.56) ATP4AATP4BAPPMAPTRAB9A
SCHEMBL8555420 1.00 ATP4A (0.56) ATP4AATP4BAPPMAPTRAB9A
SCHEMBL8557251 0.98 ATP4A (0.56) ATP4AATP4BAPPMAPTRAB9A
SCHEMBL5831354 0.93 ATP4A (0.54) ATP4AATP4BAPPMAPTRAB9A
SCHEMBL8555881 0.93 ATP4A (0.53) ATP4AATP4BAPPSULT1A1LMNA
SCHEMBL5946646 0.92 ATP4A (0.54) ATP4AATP4BAPPSULT1A1LMNA
SCHEMBL9388764 0.91 ATP4A (0.50) ATP4AATP4BAPPMAPTRAB9A
SCHEMBL10000258 0.91 ATP4A (0.56) ATP4AATP4BMAPTRAB9AL3MBTL1
SCHEMBL3724320 0.90 ATP4A (0.60) ATP4AATP4BAPPMAPTRAB9A
SCHEMBL5053235 0.90 ATP4A (0.60) ATP4AATP4BAPPMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0440061-B1 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KK (JP) 1998-04-01 EP disclosed
US-5284599-A Benzothiazole with alkyl group having asymmetric carbon connected to halogen; improved response CANON KABUSHIKI KAISHA (JP) 1994-02-08 US disclosed
US-5236619-A Benzothiazoles CANON KABUSHIKI KAISHA (JP) 1993-08-17 US disclosed
EP-0440061-A1 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KABUSHIKI KAISHA (JP) 1991-08-07 EP disclosed