Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7882222 | 0.71 | DPP4 (0.43) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL3564463 | 0.71 | DPP4 (0.43) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL1193669 | 0.69 | DPP4 (0.47) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL60955 | 0.69 | — | — | |
| SCHEMBL915178 | 0.69 | DPP4 (0.47) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL7024449 | 0.69 | DPP4 (0.41) | DPP4F2TSHRHTR2ATAAR1 | |
| Hydrochloric Acid SCHEMBL28033934 | 0.67 | DPP4 (0.45) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL377591 | 0.67 | TAAR1 (0.42) | DPP4F2TSHRTAAR1CYP2D6 | |
| SCHEMBL2406731 | 0.67 | TAAR1 (0.42) | DPP4F2TSHRTAAR1CYP2D6 | |
| SCHEMBL6923382 | 0.67 | DPP4 (0.52) | DPP4F2TSHRHTR2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831830-A4 | IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0831830-A1 | IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040143-A1 | IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |