SCHEMBL60955

SCHEMBL60955

FC(F)c1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4637121 0.82 ALDH1A1 (0.50)
SCHEMBL662302 0.81 PGK1 (0.38)
SCHEMBL915178 0.79 DPP4 (0.47)
SCHEMBL1193669 0.79 DPP4 (0.47)
Bromide SCHEMBL9813321 0.77 NOTUM (0.37)
SCHEMBL1538725 0.76 PGK1 (0.48)
SCHEMBL1538543 0.76 RXRA (0.47)
SCHEMBL24521997 0.73
SCHEMBL346424 0.73
SCHEMBL18656958 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1687 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634200-A1 ENZYMATIC SYNTHESIS OF NTP AND NQP Codexis, Inc. (US) 2025-10-22 EP claimed
WO-2025217135-A1 RNA LIGATION METHODS AND PRODUCTS CONVERGENCE BIO, INC. (US) 2025-10-16 WO claimed
US-20250122487-A1 ENGINEERED ACETATE KINASE VARIANTS CODEXIS, INC. 2025-04-17 US claimed
US-20250122486-A1 ENGINEERED ADENOSINE KINASE VARIANTS CODEXIS, INC. 2025-04-17 US claimed
WO-2025081113-A1 ENGINEERED ADENOSINE KINASE VARIANTS CODEXIS, INC. (US) 2025-04-17 WO claimed
WO-2025081095-A1 ENGINEERED ACETATE KINASE VARIANTS CODEXIS, INC. (US) 2025-04-17 WO claimed
CN-119793452-A Surface-coated Ru-based catalyst for selective hydrogenation of fluorinated aromatic hydrocarbon, and preparation method and application thereof 浙江大学衢州研究院 2025-04-11 CN claimed
CN-119306566-A Synthesis method of bromohydrogenation polycyclic aromatic hydrocarbon 浙江巨化技术中心有限公司 2025-01-14 CN claimed
CN-118932350-A Method for synthesizing carboxylic acid and deuterated carboxylic acid compound through electrochemical defluorination 江西师范大学 2024-11-12 CN claimed
CN-118507836-B Electrolyte for secondary lithium metal battery 深圳欣界能源科技有限公司 2024-09-17 CN claimed
US-5298511-A Alkanoic acid derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-03-29 US claimed
US-5288742-A Lipoxygenase inhibitor IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-02-22 US claimed
US-5217978-A Lipoxygenase inhibitors IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-06-08 US claimed
EP-0540165-A1 Alkanoic acid derivatives ZENECA LIMITED (GB) 1993-05-05 EP claimed
EP-0505122-A1 Alpha, alpha-dialkylbenzyl derivatives ZENECA LIMITED (GB) 1992-09-23 EP claimed
EP-0462812-A2 Pyran derivatives as inhibitors of 5-lipoxygenase ZENECA LIMITED (GB) 1991-12-27 EP claimed
US-5053415-A Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-01 US claimed
WO-1991013873-A1 HETEROCYCLIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1991-09-19 WO claimed
EP-0447164-A1 Heterocyclic compounds THE WELLCOME FOUNDATION LIMITED (GB) 1991-09-18 EP claimed
EP-0365328-A2 Pyridine derivatives ZENECA LIMITED (GB) 1990-04-25 EP claimed