Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GLP1R | P43220 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010959 | 0.88 | MAPT (0.58) | CYP1A2MAPTTSHRLMNAALDH1A1 | |
| SCHEMBL1734395 | 0.83 | KDM4E (0.45) | MAPTTSHRLMNAALDH1A1HTT | |
| SCHEMBL25592214 | 0.82 | TSHR (0.48) | CYP1A2TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL1179686 | 0.82 | CYP1A2 (0.46) | CYP1A2MAPTTSHRLMNAALDH1A1 | |
| SCHEMBL917429 | 0.81 | CYP1A2 (0.51) | CYP1A2MAPTTSHRS1PR2ALDH1A1 | |
| SCHEMBL2823270 | 0.81 | CYP1A2 (0.51) | CYP1A2MAPTS1PR2ALDH1A1POLB | |
| SCHEMBL5691132 | 0.80 | NPC1 (0.46) | CYP1A2MAPTLMNAS1PR2ALDH1A1 | |
| SCHEMBL19805814 | 0.80 | HTT (0.46) | MAPTTSHRLMNAALDH1A1HTT | |
| SCHEMBL1179458 | 0.79 | MAPT (0.44) | CYP1A2MAPTTSHRLMNAALDH1A1 | |
| SCHEMBL31620656 | 0.79 | MAPT (0.44) | CYP1A2MAPTTSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |