Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550932 | 0.88 | CYP1A2 (0.46) | MAPTTSHRLMNACYP1A2ALDH1A1 | |
| SCHEMBL1179686 | 0.84 | CYP1A2 (0.46) | MAPTTSHRLMNACYP1A2ALDH1A1 | |
| SCHEMBL4548034 | 0.83 | MAPT (0.59) | MAPTTSHRLMNAALDH1A1KDM4E | |
| SCHEMBL1179458 | 0.82 | MAPT (0.44) | MAPTTSHRLMNACYP1A2ALDH1A1 | |
| SCHEMBL31620656 | 0.82 | MAPT (0.44) | MAPTTSHRLMNACYP1A2ALDH1A1 | |
| SCHEMBL1178986 | 0.80 | MAPT (0.43) | MAPTTSHRLMNACYP1A2ALDH1A1 | |
| SCHEMBL9423071 | 0.80 | CYP1A2 (0.55) | MAPTCYP1A2ALDH1A1KDM4EKMT2A | |
| SCHEMBL11642670 | 0.78 | CYP1A2 (0.53) | MAPTCYP1A2ALDH1A1KDM4EKMT2A | |
| SCHEMBL14510449 | 0.78 | KMT2A (0.51) | MAPTTSHRLMNACYP1A2ALDH1A1 | |
| SCHEMBL16506338 | 0.77 | CYP1A2 (0.51) | MAPTCYP1A2ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080009622-A1 | METHOD FOR PRODUCING PYRIMIDINE COMPOUND | AJINOMOTO CO., INC. (JP) | 2008-01-10 | — | — | US | disclosed |
| EP-1849765-A1 | METHOD FOR PRODUCING PYRIMIDINE COMPOUND | Ajinomoto Co., Inc. (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009622-A1 | METHOD FOR PRODUCING PYRIMIDINE COMPOUND | TYMS, TYMP, UMPS | MAPT 4216/4885TSHR 1350/4885LMNA 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.