Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | WDR5 | P61964 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307697 | 0.92 | MAPT (0.48) | ALDH1A1CYP2C9WDR5KMT2ADDAH1 | |
| SCHEMBL29645275 | 0.92 | MAPT (0.48) | ALDH1A1CYP2C9WDR5KMT2ADDAH1 | |
| Hydrochloric Acid SCHEMBL28082928 | 0.90 | MAPT (0.47) | ALDH1A1CYP2C9WDR5KMT2ADDAH1 | |
| Hydrochloric Acid SCHEMBL2781673 | 0.90 | MAPT (0.47) | ALDH1A1CYP2C9WDR5KMT2ADDAH1 | |
| Water SCHEMBL28093018 | 0.89 | MAPT (0.46) | ALDH1A1CYP2C9WDR5KMT2ADDAH1 | |
| SCHEMBL31515444 | 0.88 | L3MBTL1 (0.36) | ALDH1A1CYP2C9WDR5KMT2ADDAH1 | |
| SCHEMBL6872706 | 0.86 | MAPT (0.38) | ALDH1A1CYP2C9WDR5KMT2ADDAH1 | |
| SCHEMBL6861334 | 0.86 | MAPT (0.35) | ALDH1A1CYP2C9WDR5KMT2ADDAH1 | |
| Hydrochloric Acid SCHEMBL8500365 | 0.85 | MAPT (0.34) | ALDH1A1CYP2C9WDR5KMT2ADDAH1 | |
| SCHEMBL8502115 | 0.84 | L3MBTL1 (0.33) | ALDH1A1CYP2C9WDR5KMT2ADDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0295603-B1 | Benzimidazol derivatives and therapeutic agent for ulcer comprising the same | EISAI CO LTD (JP) | 1996-09-18 | — | — | EP | disclosed |