SCHEMBL8551055

SCHEMBL8551055

c1coc(C2CCCCC2)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.40
ALDH1A1 P00352 5/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
ALOX15B O15296 1/20 0.35
CYP11B2 P19099 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
AURKA O14965 2/20 0.33
JAK2 O60674 2/20 0.33
PRKCA P17252 2/20 0.33
JAK1 P23458 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10419433 1.00 CYP2C19 (0.40) CYP2C19ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL16982375 1.00 CYP2C19 (0.40) CYP2C19ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL9021546 0.98 CYP2C19 (0.37) CYP2C19ALDH1A1NPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL9022156 0.96 CYP2C19 (0.36) CYP2C19ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL16397376 0.93
SCHEMBL5664401 0.89
SCHEMBL7032626 0.89 FAAH (0.31) JAK2TYK2
SCHEMBL7022546 0.85
SCHEMBL15675537 0.81 MAPK1 (0.37) MAPK1
SCHEMBL28600908 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111484526-A Optically pure 2- (diaryl phosphino) cyclohexyl oxazole ligand and preparation method thereof 南京工业大学 2020-08-04 CN claimed
CN-1317021-A Dialkyl peroxide compound and process using such for initiating chamical reaction AKZO NOBEL NV (NL) 2001-10-10 CN claimed
CN-119698422-A Aza condensed ring compound, preparation method and medical application thereof 苏州爱科百发生物医药技术有限公司 2025-03-25 CN disclosed
CN-111484526-A Optically pure 2- (diaryl phosphino) cyclohexyl oxazole ligand and preparation method thereof 南京工业大学 2020-08-04 CN disclosed
CN-106588864-A Cyclohexyl dioxolane alcohol methyl methacrylate monomer and application thereof 桂林理工大学 2017-04-26 CN disclosed
CN-100448897-C Dialkyl peroxide compound and process using such for initiating chamical reaction AKZO NOBEL NV (NL) 2009-01-07 CN disclosed
CN-1317021-A Dialkyl peroxide compound and process using such for initiating chamical reaction AKZO NOBEL NV (NL) 2001-10-10 CN disclosed
EP-0825989-A1 SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1998-03-04 EP disclosed
EP-0821675-A1 NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1998-02-04 EP disclosed
WO-1996036617-A1 SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-11-21 WO disclosed
WO-1996033176-A1 NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-10-24 WO disclosed
EP-0352909-A2 Monic acid derivatives BEECHAM GROUP PLC (GB) 1990-01-31 EP disclosed