Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.46 |
| ▸ | CA9 | Q16790 | 14/20 | 0.46 |
| ▸ | CA12 | O43570 | 11/20 | 0.46 |
| ▸ | CA1 | P00915 | 14/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.43 |
| ▸ | CTSA | P10619 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5732085 | 0.80 | CA2 (0.43) | CA2CA9CA12CA1CA14 | |
| SCHEMBL5734311 | 0.79 | CA1 (0.49) | CA2CA9CA12CA1CA14 | |
| SCHEMBL5733048 | 0.78 | CA2 (0.41) | CA2CA9CA12CA1CA14 | |
| SCHEMBL6426003 | 0.75 | CYP2D6 (0.44) | CTSA | |
| SCHEMBL5732083 | 0.70 | KMT2A (0.41) | CA2CA9CA12CA1CA14 | |
| SCHEMBL6000520 | 0.70 | CA1 (0.52) | CA2CA9CA12CA1CA14 | |
| SCHEMBL5732942 | 0.69 | CA2 (0.43) | CA2CA9CA12CA1CA14 | |
| SCHEMBL5823422 | 0.69 | CA2 (0.48) | CA2CA9CA12CA1CA14 | |
| SCHEMBL5733045 | 0.68 | DRD1 (0.40) | CA2CA9CA12CA1CA14 | |
| SCHEMBL24721510 | 0.68 | CA2 (0.68) | CA2CA9CA12CA1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |