Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550136 | 0.99 | S1PR1 (0.31) | S1PR1 | |
| SCHEMBL8549202 | 0.88 | BACE1 (0.31) | — | |
| SCHEMBL8548824 | 0.87 | TDP1 (0.35) | — | |
| SCHEMBL8550107 | 0.87 | BACE1 (0.30) | — | |
| SCHEMBL8550417 | 0.87 | RXRA (0.34) | — | |
| SCHEMBL8551649 | 0.87 | — | — | |
| SCHEMBL8553963 | 0.86 | TDP1 (0.35) | — | |
| SCHEMBL8552061 | 0.86 | — | — | |
| SCHEMBL8668305 | 0.86 | MEN1 (0.34) | — | |
| SCHEMBL8552344 | 0.85 | S1PR1 (0.30) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | claimed |