Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH1 | P20839 | 15/20 | 0.69 |
| ▸ | IMPDH2 | P12268 | 13/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546514 | 1.00 | IMPDH1 (0.69) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL1152618 | 0.97 | IMPDH1 (0.73) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL1153706 | 0.91 | IMPDH1 (0.58) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL8544680 | 0.91 | IMPDH1 (0.58) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL8545110 | 0.89 | IMPDH1 (0.55) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL8544613 | 0.89 | IMPDH1 (0.55) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL7877371 | 0.88 | IMPDH1 (0.60) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL9084374 | 0.88 | IMPDH1 (0.60) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL7877375 | 0.88 | IMPDH1 (0.60) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL1153362 | 0.88 | IMPDH1 (0.60) | IMPDH1IMPDH2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745072-B1 | 4-AMINO DERIVATIVES OF 5-SUBSTITUTED MYCOPHENOLIC ACID | SYNTEX INC (US) | 1998-05-06 | — | — | EP | disclosed |