⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592884 | 0.90 | — | — | |
| SCHEMBL8741812 | 0.85 | — | — | |
| SCHEMBL8741537 | 0.81 | — | — | |
| SCHEMBL9195875 | 0.80 | — | — | |
| SCHEMBL8741594 | 0.78 | — | — | |
| SCHEMBL8743496 | 0.77 | AR (0.31) | — | |
| SCHEMBL8741500 | 0.76 | LMNA (0.30) | — | |
| SCHEMBL8741538 | 0.76 | — | — | |
| SCHEMBL9567190 | 0.73 | — | — | |
| SCHEMBL8951396 | 0.72 | CHRM2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573289-B1 | Process for preparation of 2-oxo-1-piperidinyl derivatives | BRACCO INT BV (NL) | 1999-04-28 | — | — | EP | disclosed |
| US-5628980-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. (NL) | 1997-05-13 | — | — | US | disclosed |
| US-5614638-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. (NL) | 1997-03-25 | — | — | US | disclosed |
| US-5591846-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. | 1997-01-07 | — | — | US | disclosed |
| US-5559237-A | Process for preparation of 2-oxo-1-piperidinyl derivatives | BRACCO INTERNATIONAL B.V. (NL) | 1996-09-24 | — | — | US | disclosed |
| US-5359077-A | Process for preparation of 2-oxo-1 piperidinyl derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-10-25 | — | — | US | disclosed |
| EP-0573289-A2 | Process for preparation of 2-oxo-1-piperidinyl derivatives | BRACCO INTERNATIONAL B.V. (NL) | 1993-12-08 | — | — | EP | disclosed |