SCHEMBL8551817

SCHEMBL8551817

C=CC(=O)OCCOCCN1C(=O)C2CCCCC2C1=O

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.51
TSHR P16473 5/20 0.51
TP53 P04637 3/20 0.51
HIF1A Q16665 2/20 0.51
HSD17B10 Q99714 1/20 0.51
HTT P42858 1/20 0.41
THRB P10828 2/20 0.38
CYP3A4 P08684 1/20 0.37
RAB9A P51151 2/20 0.34
HPGD P15428 1/20 0.34
POLB P06746 1/20 0.34
PKM P14618 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL206200 0.92 HTT (0.44) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL181720 0.87 HTT (0.39) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL8552467 0.86 TSHR (0.46) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL19358623 0.81 HTT (0.40) ALDH1A1TP53HTTRAB9ATDP1
SCHEMBL10065495 0.77 TSHR (0.58) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL10065496 0.77 TSHR (0.58) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL7760723 0.76 STAT3 (0.37) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL8549222 0.76 HTT (0.42) ALDH1A1TP53HTTRAB9ATDP1
SCHEMBL1146670 0.76 ATM (0.43) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL22267294 0.75 HTT (0.33) TP53HTTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0724503-B1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING & MFG (US) 1998-11-11 EP disclosed
US-5736747-A SOLUBLE CURING AGENTS FOR PHENOLIC RESINS OR PHOTOPOLYMERIZABLE MONOMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-07 US disclosed
US-5733648-A FOR AMINOPLASTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-31 US disclosed
US-5710281-A Organic compounds suitable as reactive diluents and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5709935-A ACRYLATE FUNCTIONAL DILUENTS WHICH SOLUBILIZE AMINO RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5667842-A Abrasive articles incorporating addition polymerizable resins and reactive diluents, and methods of making said abrasive articles MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US disclosed
US-5580647-A OPEN NON-WOVEN MAT HAVING FIBERS JOINED AT POINTS OF CONTACT BY BINDER FROM ADDITION POLYMERIZABLE BINDER PRECURSOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-03 US disclosed
EP-0724503-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-07 EP disclosed
US-5523152-A Organic compounds suitable as reactive diluents, and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-04 US disclosed
WO-1995011774-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-04 WO disclosed