SCHEMBL10065496

SCHEMBL10065496

C=CC(=O)OCCOCCOCCN1C(=O)C(C)=C(C)C1=O

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.58
ALDH1A1 P00352 5/20 0.58
TP53 P04637 3/20 0.58
HIF1A Q16665 3/20 0.58
HSD17B10 Q99714 1/20 0.58
THRB P10828 2/20 0.45
HPGD P15428 1/20 0.41
PKM P14618 1/20 0.41
CYP3A4 P08684 2/20 0.41
MGLL Q99685 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10065495 1.00 TSHR (0.58) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL7047458 0.91 TSHR (0.46) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL10065490 0.84 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL17583279 0.83 TSHR (0.55) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL8052057 0.82 TSHR (0.58) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL12285609 0.81 MEN1 (0.56) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL15422957 0.80 TSHR (0.46) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL16863852 0.80 MGLL (0.52) TSHRALDH1A1HPGDPKMMGLL
SCHEMBL10065497 0.79 THRB (0.51) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL10065494 0.79 THRB (0.51) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9284461-B2 Aqueous ink composition, inkjet recording method, and inkjet printed article FUJIFILM CORPORATION (JP) 2016-03-15 US disclosed
US-20150132544-A1 INK COMPOSITION, IMAGE FORMING METHOD, AND PRINTED MATERIAL FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-20150132544-A1 INK COMPOSITION, IMAGE FORMING METHOD, AND PRINTED MATERIAL FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-8852727-B2 Ink composition, image forming method, and printed matter FUJIFILM CORPORATION (JP) 2014-10-07 US disclosed
US-8852727-B2 Ink composition, image forming method, and printed matter FUJIFILM CORPORATION (JP) 2014-10-07 US disclosed
US-8815980-B2 Ink composition for inkjet recording, inkjet recording method and printed material obtained by inkjet recording FUJIFILM CORPORATION (JP) 2014-08-26 US disclosed
US-8815980-B2 Ink composition for inkjet recording, inkjet recording method and printed material obtained by inkjet recording FUJIFILM CORPORATION (JP) 2014-08-26 US disclosed
US-20130295344-A1 INK COMPOSITION, IMAGE FORMING METHOD, AND PRINTED MATTER FUJIFILM CORPORATION (JP) 2013-11-07 US disclosed
US-20130295344-A1 INK COMPOSITION, IMAGE FORMING METHOD, AND PRINTED MATTER FUJIFILM CORPORATION (JP) 2013-11-07 US disclosed
US-20120213978-A1 INK COMPOSITION, IMAGE FORMING METHOD, AND PRINTED MATERIAL FUJIFILM CORPORATION (JP) 2012-08-23 US disclosed
US-20120213978-A1 INK COMPOSITION, IMAGE FORMING METHOD, AND PRINTED MATERIAL FUJIFILM CORPORATION (JP) 2012-08-23 US disclosed
US-20120052256-A1 AQUEOUS INK COMPOSITION, INKJET RECORDING METHOD, AND INKJET PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2012-03-01 US disclosed
US-20120052256-A1 AQUEOUS INK COMPOSITION, INKJET RECORDING METHOD, AND INKJET PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2012-03-01 US disclosed