Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 8/20 | 0.53 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | HTR6 | P50406 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8024944 | 0.99 | HSD11B1 (0.53) | HSD11B1HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8008193 | 0.91 | HTR2A (0.58) | HSD11B1HTR2AHTR2CHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL8024939 | 0.90 | HTR2A (0.57) | HSD11B1HTR2AHTR2CHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL8021166 | 0.86 | HTR2A (0.61) | HTR2AHTR2CHTR7HTR6CYP1A2 | |
| Hydrochloric Acid SCHEMBL8008644 | 0.85 | HTR2A (0.53) | HSD11B1HTR2AHTR2CHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL8025211 | 0.85 | HTR2A (0.60) | HTR2AHTR2CHTR7HTR6CYP1A2 | |
| Hydrochloric Acid SCHEMBL8025335 | 0.84 | HTR2A (0.50) | HTR2AHTR2CHTR7HTR6CYP1A2 | |
| Hydrochloric Acid SCHEMBL8008713 | 0.84 | HTR2A (0.52) | HTR2AHTR2CHTR7HTR6CYP1A2 | |
| Hydrochloric Acid SCHEMBL8025230 | 0.84 | HTR2A (0.52) | HSD11B1HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL1582857 | 0.83 | HTR2A (0.70) | HSD11B1HTR2AHTR2CHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816356-A1 | 1-(2-(1-piperidinyl)-1-ethyl)-1,3-dihydro-2H-benzimidazole derivatives and their pharmaceutical use | ELI LILLY AND COMPANY LIMITED (GB) | 1998-01-07 | — | — | EP | disclosed |