Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 6/20 | 0.53 |
| ▸ | MAOA | P21397 | 7/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557287 | 0.89 | MAOA (0.41) | CALML3MAOAMAOB | |
| SCHEMBL6403597 | 0.78 | CALML3 (0.54) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL6403602 | 0.78 | CALML3 (0.54) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL8021979 | 0.76 | MAOA (0.62) | CALML3MAOAMAOB | |
| SCHEMBL8554073 | 0.75 | MAOA (0.58) | CALML3MAOAMAOB | |
| SCHEMBL13081232 | 0.74 | CALML3 (0.52) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL541806 | 0.73 | CALML3 (0.59) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL541807 | 0.73 | CALML3 (0.59) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL3323285 | 0.73 | CALML3 (0.80) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL3323279 | 0.73 | CALML3 (0.80) | CALML3MAOAMAOBCYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856002-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997009328-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |