Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 2/20 | 0.42 |
| ▸ | FYN | P06241 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482057 | 1.00 | PRKCI (0.46) | PRKCIMKNK1MKNK2MEN1KMT2A | |
| SCHEMBL8479935 | 0.89 | PTAFR (0.49) | MEN1KMT2APTAFRPRMT5WDR77 | |
| SCHEMBL8481421 | 0.88 | MEN1 (0.52) | MEN1KMT2APTAFRALDH1A1GAA | |
| SCHEMBL8479732 | 0.88 | MEN1 (0.52) | MEN1KMT2APTAFRALDH1A1GAA | |
| SCHEMBL8477371 | 0.88 | CYP19A1 (0.50) | MKNK1MKNK2MEN1KMT2APTAFR | |
| SCHEMBL8109540 | 0.88 | MEN1 (0.52) | MEN1KMT2APTAFRALDH1A1GAA | |
| SCHEMBL8483060 | 0.88 | MEN1 (0.42) | MEN1KMT2APTAFRPRMT5WDR77 | |
| SCHEMBL8118428 | 0.88 | MEN1 (0.42) | MEN1KMT2APTAFRPRMT5WDR77 | |
| SCHEMBL8123205 | 0.88 | MEN1 (0.46) | MKNK1MKNK2MEN1KMT2APTAFR | |
| SCHEMBL8118260 | 0.88 | MEN1 (0.42) | MEN1KMT2APTAFRPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |