SCHEMBL8552004

SCHEMBL8552004

CC(=O)C(C)n1nnn(C(=O)N(c2ccc(F)cc2)C(C)C)c1=O

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.33
MC4R P32245 3/20 0.33
MC1R Q01726 3/20 0.33
KMT2A Q03164 2/20 0.32
CCKAR P32238 1/20 0.32
CCKBR P32239 1/20 0.32
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8550707 0.87 ALDH1A1 (0.41) KMT2AMEN1ALDH1A1MAPTTSHR
SCHEMBL8551420 0.87 MC4R (0.33) MC4RMC1RKMT2ACCKARCCKBR
SCHEMBL8550997 0.86 MC4R (0.33) S100A4MC4RMC1RKMT2ACCKAR
SCHEMBL8546021 0.80 MC4R (0.33) MC4RMC1RCCKARCCKBR
SCHEMBL8546092 0.79 MC4R (0.34) S100A4MC4RMC1RKMT2ACCKAR
SCHEMBL8551886 0.76 MC4R (0.32) S100A4MC4RMC1RKMT2ACCKAR
SCHEMBL8551811 0.75 MC4R (0.33) MC4RMC1RCCKARCCKBRALDH1A1
SCHEMBL8551697 0.74 ALDH1A1 (0.42) KMT2ACCKARCCKBRMEN1ALDH1A1
SCHEMBL8547220 0.74 MC4R (0.35) MC4RMC1RKMT2ACCKARCCKBR
SCHEMBL8551711 0.73 ALDH1A1 (0.41) KMT2ACCKARCCKBRMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0820994-A1 Tetrazolinones as herbicides and intermediates NIHON BAYER AGROCHEM K.K. (JP) 1998-01-28 EP disclosed