Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | IDH1 | O75874 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26121979 | 0.83 | DRD2 (0.39) | DRD2DRD3GRIN1GRIN2BCYP2D6 | |
| SCHEMBL12891739 | 0.79 | DRD2 (0.44) | DRD2DRD3GRIN1GRIN2BCYP2D6 | |
| SCHEMBL30666578 | 0.79 | DRD2 (0.44) | DRD2DRD3GRIN1GRIN2BCYP2D6 | |
| SCHEMBL10016895 | 0.79 | DRD2 (0.44) | DRD2DRD3GRIN1GRIN2BCYP2D6 | |
| SCHEMBL12891737 | 0.79 | DRD2 (0.44) | DRD2DRD3GRIN1GRIN2BCYP2D6 | |
| SCHEMBL8783210 | 0.76 | DRD2 (0.52) | DRD2DRD3GRIN1GRIN2BCYP2D6 | |
| SCHEMBL27408547 | 0.75 | DRD2 (0.41) | DRD2DRD3GRIN1GRIN2BCYP2D6 | |
| SCHEMBL31179584 | 0.75 | DRD2 (0.44) | DRD2DRD3GRIN1GRIN2BCYP2D6 | |
| SCHEMBL30279709 | 0.75 | PLAU (0.55) | DRD2DRD3GRIN1GRIN2B | |
| SCHEMBL3310824 | 0.75 | PLAU (0.55) | DRD2DRD3GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |