Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556455 | 0.86 | ALOX5 (0.34) | ALOX5 | |
| SCHEMBL2106820 | 0.81 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL8553537 | 0.78 | ALOX5 (0.36) | ALOX5 | |
| SCHEMBL9371449 | 0.74 | ALOX5 (0.40) | ALOX5 | |
| SCHEMBL8556706 | 0.73 | — | — | |
| SCHEMBL8556618 | 0.73 | — | — | |
| SCHEMBL2107107 | 0.73 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9277272 | 0.71 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL9277268 | 0.71 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL1445372 | 0.70 | ALOX5 (0.41) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623614-B1 | 4-Aryl-4-hydroxy-tetrahydropyrans and 3-aryl-3-hydroxy-tetrahydrofurans as 5-lipoxygenase inhibitors | ZENECA LTD (GB) | 1998-02-25 | — | — | EP | claimed |