Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992818 | 0.87 | ABCB1 (0.36) | ABCB1ABCC1HRH1SMN1; SMN2LMNA | |
| SCHEMBL8589743 | 0.83 | LMNA (0.35) | ABCB1ABCC1HRH1SMN1; SMN2LMNA | |
| SCHEMBL6995389 | 0.82 | KMT2A (0.39) | ABCB1ABCC1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL6994509 | 0.82 | KMT2A (0.37) | ABCB1ABCC1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL7003238 | 0.80 | TSHR (0.33) | HRH1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL7002664 | 0.79 | HRH1 (0.40) | HRH1SMN1; SMN2LMNAPDE4APDE4B | |
| SCHEMBL7000714 | 0.78 | SMN1; SMN2 (0.41) | HRH1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL7961305 | 0.77 | KDM4E (0.39) | HRH1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL6997660 | 0.77 | MAPK1 (0.39) | HRH1KMT2AMEN1PDE4APDE4B | |
| SCHEMBL8317975 | 0.77 | MAPK1 (0.37) | HRH1SMN1; SMN2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874843-A1 | NOVEL SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL) 1,4]DIAZEPANES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997022604-A1 | NOVEL SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL)[1,4]DIAZEPANES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1997-06-26 | — | — | WO | disclosed |