Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476865 | 1.00 | MEN1 (0.45) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL8479732 | 0.90 | MEN1 (0.52) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL8477371 | 0.90 | CYP19A1 (0.50) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL8109540 | 0.90 | MEN1 (0.52) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL8481421 | 0.90 | MEN1 (0.52) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL8483060 | 0.90 | MEN1 (0.42) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL8118428 | 0.90 | MEN1 (0.42) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL8118260 | 0.90 | MEN1 (0.42) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL7829887 | 0.88 | MEN1 (0.45) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL8482114 | 0.88 | NPC1 (0.48) | MEN1KMT2AALDH1A1ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |