Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | PRCP | P42785 | 2/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | BACE1 | P56817 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516300 | 0.76 | HTR2A (1.00) | DRD4HTR2ADRD2DRD3MEN1 | |
| Hydrochloric Acid SCHEMBL8552262 | 0.75 | HTR2A (0.98) | DRD4HTR2ADRD2DRD3MEN1 | |
| SCHEMBL8556407 | 0.73 | DRD4 (0.59) | DRD4HTR2AMAPK14KDM4EMEN1 | |
| SCHEMBL8558550 | 0.72 | HTR2A (0.59) | DRD4HTR2APRCPDRD2HTR6 | |
| SCHEMBL8557341 | 0.71 | PRCP (0.55) | DRD4PRCPDRD2DRD3ALDH1A1 | |
| SCHEMBL19493714 | 0.70 | SLC18A3 (0.70) | DRD4ACHEBCHEBACE1SLC18A3 | |
| SCHEMBL8434654 | 0.70 | DRD4 (0.52) | DRD4HTR2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8554786 | 0.69 | HTR2A (0.47) | DRD4HTR2AMAPK14 | |
| SCHEMBL22778175 | 0.68 | CNR2 (0.60) | DRD4HTR2AACHEBCHEBACE1 | |
| SCHEMBL22795424 | 0.68 | CNR2 (0.60) | DRD4HTR2AACHEBCHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816362-A1 | THIAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1998-01-07 | — | — | EP | disclosed |