Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553513 | 0.84 | HTR2A (0.59) | HTR2ADRD4DRD2HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL8556568 | 0.83 | HTR2A (0.58) | HTR2ADRD4DRD2HTR7HTR6 | |
| SCHEMBL6907364 | 0.75 | HTR2A (1.00) | HTR2ADRD4DRD2 | |
| SCHEMBL7516300 | 0.75 | HTR2A (1.00) | HTR2ADRD4DRD2 | |
| Hydrochloric Acid SCHEMBL8552262 | 0.74 | HTR2A (0.98) | HTR2ADRD4DRD2 | |
| SCHEMBL8552184 | 0.72 | DRD4 (0.61) | HTR2ADRD4DRD2HTR6PRCP | |
| Bromide SCHEMBL8553366 | 0.71 | HTR2A (0.91) | HTR2ADRD4DRD2 | |
| SCHEMBL8552863 | 0.69 | HTR2A (0.87) | HTR2ADRD4DRD2 | |
| SCHEMBL6898517 | 0.67 | HTR2A (0.46) | HTR2ADRD4DRD2HTR6PRCP | |
| SCHEMBL8556407 | 0.65 | DRD4 (0.59) | HTR2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816362-A1 | THIAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1998-01-07 | — | — | EP | disclosed |