Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 11/20 | 0.40 |
| ▸ | HTR2A | P28223 | 10/20 | 0.40 |
| ▸ | HTR2B | P41595 | 9/20 | 0.40 |
| ▸ | HTR1A | P08908 | 6/20 | 0.38 |
| ▸ | HTR1D | P28221 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27500349 | 0.81 | MTNR1A (0.42) | MTNR1AMTNR1BHTR2CHTR2AHTR2B | |
| SCHEMBL28218012 | 0.80 | MTNR1A (0.41) | MTNR1AMTNR1BHTR2CHTR2AHTR2B | |
| SCHEMBL6950651 | 0.78 | HTR2C (0.47) | MTNR1AMTNR1BHTR2CHTR2AHTR2B | |
| SCHEMBL20554279 | 0.77 | HTR2C (0.44) | MTNR1AMTNR1BHTR2CHTR2AHTR2B | |
| SCHEMBL20669648 | 0.77 | MTNR1A (0.41) | MTNR1AMTNR1BHTR2CHTR2AHTR2B | |
| SCHEMBL8463358 | 0.77 | MTNR1A (0.41) | MTNR1AMTNR1BHTR2CHTR2AHTR2B | |
| SCHEMBL6682400 | 0.77 | MTNR1A (0.44) | MTNR1AMTNR1BHTR2CHTR2AHTR2B | |
| SCHEMBL21872018 | 0.77 | MTNR1A (0.47) | MTNR1AMTNR1BHTR2CHTR2AHTR2B | |
| SCHEMBL30289569 | 0.77 | HTR2C (0.44) | MTNR1AMTNR1BHTR2CHTR2AHTR2B | |
| SCHEMBL6950648 | 0.75 | MTNR1A (0.46) | MTNR1AMTNR1BHTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859776-A1 | COMPOUNDS DERIVED FROM OXAZOLIDIN-2-ONE AND PREPARATION AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017347-A1 | COMPOUNDS DERIVED FROM OXAZOLIDIN-2-ONE AND PREPARATION AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-05-15 | — | — | WO | disclosed |