Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | F2R | P25116 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 3/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662823 | 0.85 | ABL1 (0.54) | ABL1F2RKCNH3EPHX1HTT | |
| SCHEMBL22176875 | 0.82 | ABL1 (0.53) | ABL1F2RKCNH3EPHX1HTT | |
| SCHEMBL8667014 | 0.79 | F2R (0.56) | KDM4EABL1F2RKCNH3HTT | |
| SCHEMBL21799532 | 0.79 | TSHR (0.50) | KDM4EABL1F2RKCNH3EPHX1 | |
| SCHEMBL21799643 | 0.79 | TSHR (0.50) | KDM4EABL1F2RKCNH3EPHX1 | |
| SCHEMBL21799443 | 0.79 | TSHR (0.50) | KDM4EABL1F2RKCNH3EPHX1 | |
| SCHEMBL3397885 | 0.79 | TSHR (0.50) | KDM4EABL1F2RKCNH3EPHX1 | |
| SCHEMBL21799916 | 0.79 | TSHR (0.50) | KDM4EABL1F2RKCNH3EPHX1 | |
| SCHEMBL21799446 | 0.79 | TSHR (0.50) | KDM4EABL1F2RKCNH3EPHX1 | |
| SCHEMBL5604882 | 0.79 | TSHR (0.50) | KDM4EABL1F2RKCNH3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11158150-A | — | — | None | — | — | JP | disclosed |
| JP-H11158150-A | 5-AMINO-1-CYCLOPROPYL-4-OXOQUINOLINE-3-CARBOXYLIC ACID DERIVATIVE AND ITS PREPARATION | IHARA CHEM IND CO LTD | 1999-06-15 | — | — | JP | disclosed |