Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715739 | 0.83 | SIGMAR1 (0.43) | TAAR1SIGMAR1TRPA1SLC6A2SLC6A4 | |
| SCHEMBL9186461 | 0.82 | TAAR1 (0.59) | TAAR1SIGMAR1TRPA1SLC6A2SLC6A4 | |
| SCHEMBL1403749 | 0.77 | EPHX1 (0.41) | SIGMAR1TRPA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3016224 | 0.75 | SIGMAR1 (0.45) | TAAR1SIGMAR1TRPA1SLC6A2SLC6A4 | |
| SCHEMBL16245523 | 0.75 | TAAR1 (0.43) | TAAR1SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL3151286 | 0.72 | KMT2A (0.36) | TAAR1TRPA1ADRA2CCYP2D6 | |
| SCHEMBL27565354 | 0.72 | EPHX1 (0.51) | — | |
| SCHEMBL8333871 | 0.72 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL11028204 | 0.72 | TAAR1 (0.52) | TAAR1SIGMAR1TRPA1SLC6A2SLC6A4 | |
| SCHEMBL18531114 | 0.70 | KDM4E (0.46) | TAAR1SIGMAR1TRPA1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |