Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546560 | 0.93 | ALDH1A1 (0.42) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL6965178 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6969794 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL8593312 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL6981306 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL6969560 | 0.77 | SLC18A3 (0.40) | POLB | |
| Hydrochloric Acid SCHEMBL6980655 | 0.76 | SLC18A3 (0.39) | — | |
| SCHEMBL6975587 | 0.76 | SLC18A3 (0.39) | POLB | |
| SCHEMBL6968410 | 0.75 | HRH3 (0.43) | ALDH1A1L3MBTL1TSHRMAPTPOLB | |
| SCHEMBL8552646 | 0.74 | CA1 (0.41) | ALDH1A1KDM4EMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-A1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-02-04 | — | — | EP | claimed |