Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964478 | 0.80 | — | — | |
| SCHEMBL9093259 | 0.80 | TAAR1 (0.33) | — | |
| SCHEMBL8548954 | 0.79 | — | — | |
| Trifluoroacetic Acid SCHEMBL6977922 | 0.71 | CYP1A2 (0.34) | — | |
| SCHEMBL9093961 | 0.71 | EPHX1 (0.32) | — | |
| SCHEMBL8552530 | 0.70 | — | — | |
| SCHEMBL8554740 | 0.63 | MEN1 (0.32) | — | |
| SCHEMBL6975038 | 0.62 | — | — | |
| SCHEMBL6975043 | 0.62 | — | — | |
| SCHEMBL6969288 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824523-A1 | NITRIC OXIDE SYNTHASE INHIBITORS DERIVED FROM CYCLIC AMIDINES | G.D. Searle & Co. (US) | 1998-02-25 | — | — | EP | disclosed |