Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9093259 | 0.78 | TAAR1 (0.33) | — | |
| SCHEMBL9095135 | 0.73 | — | — | |
| SCHEMBL9095127 | 0.73 | — | — | |
| SCHEMBL6973304 | 0.69 | MAPT (0.35) | — | |
| SCHEMBL8552805 | 0.63 | KDM4E (0.30) | — | |
| SCHEMBL9093806 | 0.63 | NPC1 (0.35) | MEN1KMT2A | |
| SCHEMBL6976764 | 0.62 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL6970182 | 0.60 | SLC6A3 (0.39) | SLC1A2SLC1A1 | |
| SCHEMBL17434128 | 0.59 | PTGS1 (0.50) | KMT2AGRM2GRM3SLC1A2SLC1A1 | |
| SCHEMBL6969217 | 0.59 | SLC6A2 (0.36) | MEN1KMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824523-A1 | NITRIC OXIDE SYNTHASE INHIBITORS DERIVED FROM CYCLIC AMIDINES | G.D. Searle & Co. (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035677-A1 | NITRIC OXIDE SYNTHASE INHIBITORS DERIVED FROM CYCLIC AMIDINES | G.D. SEARLE & CO. (US) | 1996-11-14 | — | — | WO | disclosed |