Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.65 |
| ▸ | RXRB | P28702 | 17/20 | 0.65 |
| ▸ | RXRG | P48443 | 14/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.65 |
| ▸ | C5 | P01031 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.65 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098559 | 0.93 | RXRA (0.60) | RXRARXRBRXRGNR4A2KDM4E | |
| SCHEMBL5732078 | 0.92 | RXRA (0.76) | RXRARXRBRXRGNR4A2KDM4E | |
| SCHEMBL5732939 | 0.92 | RXRA (0.76) | RXRARXRBRXRGNR4A2KDM4E | |
| SCHEMBL7498736 | 0.90 | CA1 (0.60) | RXRARXRBRXRGNR4A2KDM4E | |
| SCHEMBL7499819 | 0.90 | CA1 (0.60) | RXRARXRBRXRGNR4A2KDM4E | |
| SCHEMBL5733196 | 0.88 | RXRA (0.77) | RXRARXRBRXRGNR4A2KDM4E | |
| SCHEMBL5733040 | 0.88 | RXRA (0.77) | RXRARXRBRXRGNR4A2KDM4E | |
| SCHEMBL8547300 | 0.87 | RXRA (0.78) | RXRARXRBRXRGNR4A2KDM4E | |
| SCHEMBL8550151 | 0.86 | RXRA (0.76) | RXRARXRBRXRGNR4A2KDM4E | |
| SCHEMBL8552927 | 0.84 | RXRA (0.58) | RXRARXRBRXRGNR4A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |