Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | CRHBP | P24387 | 3/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552995 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1CRHBPCRHR2 | |
| Hydrochloric Acid SCHEMBL8548612 | 0.98 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1CRHBPCRHR2 | |
| Hydrochloric Acid SCHEMBL8548617 | 0.98 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL19480058 | 0.82 | MAPK1 (0.53) | ALDH1A1KMT2AMEN1CRHBPCRHR2 | |
| Oxalic Acid SCHEMBL6844280 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1CRHBPCRHR2 | |
| Oxalic Acid SCHEMBL6844283 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL2086648 | 0.76 | MAPK1 (0.56) | ALDH1A1KMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL12545552 | 0.76 | MAPK1 (0.56) | ALDH1A1KMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL18820626 | 0.75 | MAPK1 (0.56) | ALDH1A1KMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL14505847 | 0.75 | MAPK1 (0.56) | ALDH1A1KMT2AMEN1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846689-A1 | Benzimidazole compounds | PFIZER INC. (US) | 1998-06-10 | — | — | EP | disclosed |