Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8555901 | 0.87 | HTT (0.32) | HTTKMT2A | |
| SCHEMBL9094834 | 0.80 | HTT (0.33) | HTTKMT2A | |
| SCHEMBL8556610 | 0.77 | HCRTR2 (0.33) | KMT2A | |
| SCHEMBL8555358 | 0.76 | KMT2A (0.30) | KMT2APDK2 | |
| SCHEMBL8558031 | 0.75 | PDK2 (0.32) | PDK2 | |
| SCHEMBL8554977 | 0.71 | PRKAB2 (0.34) | KMT2APDK2 | |
| Hydrochloric Acid SCHEMBL8557102 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL8553946 | 0.70 | PRKAB2 (0.34) | — | |
| SCHEMBL9095427 | 0.69 | HTT (0.35) | HTT | |
| SCHEMBL8558902 | 0.69 | SIRT2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653426-B1 | Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same | KOWA CO (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5510366-A | INOTROPIC, ANTIARRHYMTHMIA AGENTS, VASODILATORS | KOWA CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0653426-A1 | Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same | KOWA COMPANY, LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |